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"Bisphenol A" Exposure Affects Subsequent Generations

Professor Bang Myung-geol's research team at the Korea Institute of Life and Environment found that health and reproductive risks caused by exposure to bisphenol A affect subsequent generations through a multi-generation study using mice.


Bisphenol A is the most frequently exposed substance in daily life among endocrine disruptors called environmental hormones, and is known to cause health and reproductive hazards, but it has not been proven to spread to the next generation.


The research team explained that the reproductive risk caused by bisphenol A exposure occurs when fetal-related proteins are mutated by the epigenetic regulation of sperm genes (DNA).


It was also confirmed that reproductive risk is transmitted from the first generation to the second generation, but not to the third generation.


Professor Bang, the research director, said, "Even if it takes some time, maintaining the environment of de-environmental hormones can minimize the risk of reproduction and health of the next generation. This research result will serve as an opportunity to conduct multigenerational research on reproductive diseases such as cancer, diabetes, and high blood pressure."


Writer: Linda Chen


(Picture from Unsplash)


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